This study investigates the effect of various digital technologies on employee performance in public hospitals located in the headquarters of the three senatorial zones in Niger State, Nigeria. The employed survey design that is cross-sectional in nature. The population consist of 502 hospital employees, from whom a sample of 217 was purposively and randomly selected following Krejcie and Morgan’s (1970) guideline to ensure both statistical validity and practical feasibility. A total of 209 copies of questionnaire were returned and analysed to assess how hardware, software, database, and network technologies influence job performance among healthcare workers through multiple linear regression. Findings reveal that database and network technologies positively and significantly enhance employee performance, while hardware technology has a negative effect, and software technology shows no significant impact. These results highlight critical areas for ICT investment and capacity-building in public healthcare settings to improve workforce productivity and service delivery.